The RainDrop® Digital PCR System is the industry’s most sensitive instrument for researching nucleic acid detection and disease monitoring. Capable of producing up to 10 million picoliter sized droplets, the RainDrop Digital PCR System surpasses all existing technologies and establishes a new performance standard in low-frequency tumor allele detection. In this webinar, researchers will focus on assay sensitivity for 18 different cancer-related mutations, which range from 1 : 10,000 to better than 1 : 1 million. In this webinar, we discussed the statistics and methodology, as well as assay design and DNA sample properties.
Coren Milbury is a Senior Scientist in the Genomics Applications R&D group at RainDance since 2011. She has been involved in optimizing reactions, reagents, and assays for the RainDrop Digital PCR system. Cori received her bachelor’s degree at the University of New Hampshire, and her masters and PhD degrees from the University of Delaware.
Brian Hutchison manages the Advanced Technologies Group and he has been participating in the development of droplet microfluidics technology and applications at RainDance since 2006. He and his team focus on integration of consumables and reagents with instrumentation and data analysis to enable digital PCR and sequence enrichment applications. During the past few years, he has led a RainDance team in a collaboration with scientists at Universite Paris – Descartes to apply digital PCR technology to detect mutations in DNA from solid tumors and circulating DNA. This collaboration has resulted in three publications so far (Clin Chem 59(5) 815-823, Clin Chem 59(12) 1722-1731, Clin Canc Res 10.1158/1078-0432). Brian received a bachelor’s degree in Chemical Engineering from the University of Delaware and a PhD in Chemical and Biological Engineering from the University of Colorado.