ThunderStorm™ System
Fully automated, high-throughput targeted sequencing system
The RainDance ThunderStorm™ System is a fully automated, high-throughput targeted sequencing solution that enables researchers to process more samples per day and generate higher-quality data faster than ever before. The system features true walkaway capabilities, automatically processing up to 96 samples and accessing up to eight different primer panels. The ThunderStorm System leverages RainDance’s proven single-molecule picodroplet PCR technology that generates millions of unique picodroplet PCR reactions, enabling scientists to target up to 20,000 genomic loci in a single sample. The RainDance ThunderStorm System combines premium performance and a proven technology platform to deliver unprecedented daily sample throughput with the most attractive running economics and minimal hands-on time.
Highlights
Fully automated high-throughput targeted sequencing system
- 1 to 96 samples per run
Extremely Versatile
- Ability to screen 96 samples against 8 different primer panels
Compatible with all NGS platforms
- Illumina’s HiSeq™ and MiSeq™
- Ion Torrent’s PGM™
- Life’s 5500 SOLiD™
- PacBio’s RS
- Roche’s GS FLX™ and GS Junior™ Systems
Broad range of applications: GWAS follow up, medical genetics, somatic mutation analysis, epigenetics
Low cost per sample: high-volume chips manufactured by Sony DADC, elimination of sequencing library costs
Highest quality data: proven RainDance sequence coverage and uniformity
Fully Automated Instrumentation
ThunderStorm™ System Advantages
- Comprehensive genomic coverage: Determine all variation contained in any desired region of the genome
- Unparalleled target selection: Increased accuracy and greater coverage uniformity; requires less sequencing per sample than alternative enrichment methods
- Production ready for clinical research lab: Enable high-throughput screening and validation for mutation analysis and interpretation for genetic disorders using next-generation sequencing
- Reduced sample input requirements: Use as little as 250ng of unamplified genomic DNA
- Elimination of downstream NGS library processing: Integrate sequencing adaptors directly into sequence-ready targets with RainDance’s DirectSeq workflow™ using tailed primers
- Fast turnaround and simple workflow: Generate sequence-ready samples in as little as 4 hours from sample to sequencer
- Designed for the future: Enabled for amplicon sizes from 150bp – 1.5kb today and up to ~10 kb in the future
Thunderstorm Video: "Fully Automated"
Ambry Genetics offers an inside look at RainDance's new fully-automated, high-throughput targeted sequencing system.
Targeted DNA Sequencing Customers
