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Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR Jennifer B. Jackson,* Daniel S. Choi,* James D. Luketich,* Arjun Pennathur,* Anders Ståhlberg,* and Tony E. Godfrey*
Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers Elena Pereira1, Olga Camacho-Vanegas2, Sanya Anand2, Robert Sebra2, Sandra Catalina Camacho2, Leopold Garnar-Wortzel2, Navya Nair1, Erin Moshier4, Melissa Wooten2,
Determining lower limits of detection of digital PCR assays for cancer-related gene mutations Coren A. Milbury, Qun Zhong, Jesse Lin, Miguel Williams, Jeff Olson, Darren R. Link, Brian Hutchison – DOI: 10.1016/j.bdq.2014.08.001
Clinical relevance of KRAS-mutated sub-clones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy Pierre Laurent-Puig, Deniz Pekin, Corinne Normand, Steve K. Kotsopoulos, Philippe Nizard, Karla Perez Toralla, Rachel Rowe, Jeff Olson, Pree
Assessment of droplet digital PCR for absolute quantification of genetically engineered OXY235 canola and DP305423 soybean samples Tom Gräfenhan, Michelle Holigroski,Ursla Fernando, Janice Bamforth, Sung-Jong Lee; Canadian Grain Commission, Grain Research Laboratory, 1404-303 Main St,
Emerging technologies in extracellular vesicle-based molecular diagnostics Shidong Jia, Davide Zocco, Michael L Samuels, Michael F Chou, Roger Chammas, Johan Skog, Natasa Zarovni, Fatemeh, Momen-Heravi, and Winston Patrick Kuo
Multiplex Picoliter-Droplet Digital PCR for Quantitative Assessment of DNA Integrity in Clinical Samples Audrey Didelot1, Steve K. Kotsopoulos2, Audrey Lupo1, Deniz Pekin1, Xinyu Li, Ivan Atochin, Preethi Srinivasan, Qun Zhong, Jeff Olson, Darren R. Link, Pierre Laurent-Puig, Hélène B
Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis Mazutis L, Araghi AF, Miller OJ, Baret JC, Frenz L, Janoshazi A, Taly V, Miller BJ, Hutchison JB, Link D, Griffiths AD, Ryckelynck M. Citation: Anal Chem. 2009
RainDance Technologies is making complex genetics simple. The company’s ultra-sensitive genomic tools enable research of novel non-invasive liquid biopsy applications that should result in more accurate, reliable, cost-effective, and early detection of cancer and other inherited and infectious diseases. Major research institutions and laboratories around the world rely on the performance of RainDance systems. Based outside Boston, Massachusetts, the company supports customers using RainDrop® Digital PCR, as well as the ThunderStorm® and ThunderBolts™ Next-Generation Sequencing Enrichment Systems through its international sales and service operations, as well as a global network of distributors and commercial service providers. Both technology platforms have been recognized by The Scientist as Top 10 Innovations with the RainDrop System winning the award in 2014 and the ThunderStorm System winning the award in 2011.